Hi Steve, I thought I would re-post the information given to me recently by Dionigi which saved my nijsseni Hope you can save them, I long been on the lookout for Apistogrammoides without success. Ken. Ken Laidlaw <wrote: <<<<< My previously healthy pair of A.nijsseni have stopped feeding. They were fine until a week ago when they just seemed to lose interest in food. I have a guppy in the tank as a dither and it is fine and feeding. I have fed some live food, bloodworms and daphnia but these were also fed to my panduro and they are OK. I have done a couple of water changes (water pH=6.5) over the last couple of days and added a treatment for internal bacterial disease. (...)>>>>>>> Ken, bacterial diseases are relatively less likely to manifest themselves as lack of appetite only. This type of symptom is more typically due to Hexamita (Spironucleus) or intestinal worms, and occasionally to skin or gill parasites. Metronidazole and a broad spectrum de-wormer (flubenol for example) would be my first choice, followed by formalin+malachite green (for skin and gill protozoans, carefully using the dosages and precautions listed on fish health books) if there is no prompt improvement with the former two medications. Dionigi My reply after treatment...... Dionigi, Thanks for your tips, my A.nijsseni have recovered and are now eating well. Here is what I did following your advice. I treated them with levamisole hydrochloride to try and purge any internal parasites present. I also treated with Octozin (TM) which claims to cure Hexamita. Metranizadole or any anti-biotics are not available without prescription here in the UK. Thanks for your help, let's hope they have a successful spawn soon. Regards, Ken.