"Robert J Molan" wrote: <<<<< Need advice on skin lesion in P taenitus One of my P taenitus species has developed a lesion at the base of the dorsal fin. The lesion is ulcerated and is not responding to conservative treatment, starting at salt baths, and antifungal/finrot medications. My question is should I use antibiotics on her, or should I continue to treat in conservative fashion. Also although she is moved to a hospital tank should I treat her old tank.>>>>>>> I do not think you need to treat the previous tank. Several skin ulcerations are not treatable (actually, in some cases they may be infective to humans, and caution should be exercised in immersing bare hands in tanks with fishes in this condition), and it is my impression that water quality is the key factor that the average hobbyist may control. Antibiotics just dispersed in the water may not be too effective, but if you suspect a bacterial origin (red, swollen lesions) you can give a try for example with one of the furans, such as nifurpirinol. (Steven J. Waldron wrote: <<<<<Parasitized Apistogrammoides I recently picked up some Apistogrammoides pucallpaensis and after a few weeks of what seemed to be excellent health and vigor, they are starting to go down. None have died as of yet, but they have stopped eating, feces are stringy, bellies pinched, and a lot of time spent sitting on the bottom of the aquarium.(...) I have been treating with Paragon II, an anit-parasite med that contains metrondiazole. Things seem to be getting progressively worse (...) >>>>> Steve, Paragon is in my opinion a poorly effective and poorly tolerated drug, due to the choice of the ingredients. It is supposed to work by the "shotgun" approach, but the only victims are normally the bacteria in the biological filter, and occasionally the sick fish! Clean it out with carbon, and then go on with a de-wormer such as Fluke-Tabs (one full dose only) or flubenol (I assume you are in the US, where either one is more easily available than other possible choices). A temperature in the low eighties might be of some support. If this does not work, try again metronidazole at full dose(use for example the formulation from Aquatronics). Dionigi Maladorno dionigi.maladorno@roche.com This message presents personal opinions which are not necessarily those of my employer.